Switch of glycolysis to gluconeogenesis by dexamethasone

gluconeogenesis  The problem for Gluconeogenesis was that the enzymes hexokinase and PFK were irreversible Gluconeogenesis is an overall exergonic process which may seem confusing since glucose is being formed However, note in the reaction equation that there are

Gluconeogenesis is the creation of glucose molecules from non-sugar precursors This process takes place predominately in hepatocytes and to Gluconeogenesis is not simply the reverse of glycolysis; it utilizes unique enzymes (pyruvate carboxylase, PEPCK, fructose-1,6- bisphosphatase, and glucose-6-

Dexamethasone, an active form of synthesized glucocorticoids, is capable of restoring gluconeogenesis in malignant cells by bypassing the Gluconeogenesis occurs in the liver and kidneys The gluconeogenesis pathway helps maintain blood glucose levels during fasting or low